New paper in Nature Communications

Following the movement of a protein is often extremely important to understand its function. Membrane transporters, for example, undergo a series of complicated movements to translocate a substrate. Two techniques that are often used to study such movements are PELDOR/DEER and smFRET. Both techniques can measure distances on the nanometer scale. In collaboration with the laboratory of Thorben Cordes at the LMU Munich, Martin and Gregor have compared the accuracy of the two methods on three different substrate binding proteins. The study has just been published in Nature Communications.