Together with Sneha Singh, Arijit Biswas and Johannes Oldenburg from the Institute of Hematology, Gregor and Matthias determined the first structure of the A and B subunits of Factor XIII. This tetrameric protein complex plays an important role in blood coagulation and is linked to many bleeding disorders. Using single particle cryo-EM, we were able to resolve the FXIII-A2B2 complex at 2.4 Å resolution. Read all about this exciting story here.
